Dr. Antony Jose published in Nature Communications

Researchers from UMD found that the same gene for expressing a red fluroscent protein is always express (ON), when it is inherited from the mother, but when inherited from the father can lose expression (turn OFF) forever if the mother lacks the gene.
Researchers from UMD found that the same gene for expressing a red fluroscent protein is always express (ON), when it is inherited from the mother, but when inherited from the father can lose expression (turn OFF) forever if the mother lacks the gene.

Congratulations to Antony Jose whose paper was published today in Nature Communications. Antony’s recent study provides a potential tool for unraveling the mystery of how an animal’s lived experience can be passed down through generations.

 

While breeding nematode worms, Jose and his team found that some matings led to epigenetic changes in offspring that continued to be passed down through as many generations as the scientists continued to breed them. This discovery will enable scientists to explore how epigenetic changes are passed to future generations and what characteristics make genes susceptible to permanent epigenetic changes.

 

Read more here: https://cmns.umd.edu/news-events/features/4812

 

The research paperMating can initiate stable RNA silencing that overcomes epigenetic recovery, Sindhuja Devanapally, Pravrutha Raman, Mary Chey, Samual Allgood, Farida Ettefa, Maïgane Diop, Yixin Lin, Yongyi E Cho, and Antony M Jose, was published on July 9, 2021, in the journal Nature Communications.