Kan Cao headshot
Contact Info
Office: 2114 Bioscience Research Bldg
Phone: 301-405-3016
Kan Cao
Professor
Associate Chair

Biography

Kan Cao, Ph.D. received her B.S. in Biology from Nanjing University and her Ph.D. in Biology from Johns Hopkins University. She completed postdoctoral training in genomics at the National Institutes of Health. Dr. Cao is a Professor and Associate Chair of Cell Biology and Molecular Genetics at the University of Maryland.

Dr. Cao’s research focuses on the molecular and cellular mechanisms of Hutchinson–Gilford Progeria Syndrome (HGPS), a rare premature aging disorder, and fundamental processes of human aging. Her work has contributed to understanding how mutations in the lamin A gene disrupt nuclear architecture and drive disease, with broader implications for laminopathies and age-related pathologies. Her laboratory integrates cell biology, stem cell models, and genomic approaches to study nuclear structure and function. Her contributions have been recognized with multiple honors, including the Ellison Medical Foundation New Scholar in Aging Award, University of Maryland faculty awards, entrepreneurship distinctions, and induction as a Senior Member of the National Academy of Inventors.


Graduate Program Affiliations

  • BISI-Molecular & Cellular Biology (MOCB)  

Research Interests

Hutchinson Gilford progeria, telomere and cellular senescence, alternative splicing and human aging


Education

  • Ph.D., Johns Hopkins University, 2005

All Publications

Google Scholar logo    Pubmed logo


Latest Publications

Gentry E,Islam MT,Xue H,Cao K,Nemes P
Mol Cell Proteomics. 2025 Dec 17;:101490. doi: 10.1016/j.mcpro.2025.101490. Epub 2025 Dec 17
Gates SJ 3rd,Alvarez PH,O'Neill KM,Cao K,Losert W
Commun Biol. 2025 Jul 1;8(1):978. doi: 10.1038/s42003-025-08342-y. Epub 2025 Jul 1
Abutaleb NO,Gao XD,Bedapudi A,Choi L,Shores KL,Kennedy C,Duby JE,Cao K,Liu DR,Truskey GA
APL Bioeng. 2025 Mar;9(1):016110. doi: 10.1063/5.0244026. Epub 2025 Feb 26
Vakili S,Izydore EK,Losert L,Cabral WA,Tavarez UL,Shores K,Xue H,Erdos MR,Truskey GA,Collins FS,Cao K
Aging Cell. 2025 Feb;24(2):e14375. doi: 10.1111/acel.14375. Epub 2024 Oct 18
Vakili S,Cao K
Int J Mol Sci. 2024 Dec 18;25(24):. doi: 10.3390/ijms252413537. Epub 2024 Dec 18
Yu R,Xue H,Lin W,Collins FS,Mount SM,Cao K
NAR Genom Bioinform. 2024 Sep;6(3):lqae115. doi: 10.1093/nargab/lqae115. Epub 2024 Aug 29
Xue H,Gate S 3rd,Gentry E,Losert W,Cao K
Sci Rep. 2023 Oct 26;13(1):18384. doi: 10.1038/s41598-023-45826-5. Epub 2023 Oct 26
Abutaleb NO,Atchison L,Choi L,Bedapudi A,Shores K,Gete Y,Cao K,Truskey GA
Sci Rep. 2023 Mar 28;13(1):5032. doi: 10.1038/s41598-023-32035-3. Epub 2023 Mar 28
Xue H,Cao K
Nat Aging. 2023 Feb;3(2):146-147. doi: 10.1038/s43587-022-00351-4. Epub
Mao X,Xiong ZM,Xue H,Brown MA,Gete YG,Yu R,Sun L,Cao K
Int J Mol Sci. 2022 May 14;23(10):. doi: 10.3390/ijms23105499. Epub 2022 May 14
Xue H,Thaivalappil A,Cao K
Cells. 2021 Dec 1;10(12):. doi: 10.3390/cells10123379. Epub 2021 Dec 1
Fields E,Vaughan E,Tripu D,Lim I,Shrout K,Conway J,Salib N,Lee Y,Dhamsania A,Jacobsen M,Woo A,Xue H,Cao K
Ageing Res Rev. 2021 Sep;70:101385. doi: 10.1016/j.arr.2021.101385. Epub 2021 Jun 5
Gete YG,Koblan LW,Mao X,Trappio M,Mahadik B,Fisher JP,Liu DR,Cao K
Aging Cell. 2021 Jul;20(7):e13388. doi: 10.1111/acel.13388. Epub 2021 Jun 4
Xiong ZM,Mao X,Trappio M,Arya C,Kordi JE,Cao K
Sci Rep. 2021 May 28;11(1):10871. doi: 10.1038/s41598-021-89970-2. Epub 2021 May 28
Erdos MR,Cabral WA,Tavarez UL,Cao K,Gvozdenovic-Jeremic J,Narisu N,Zerfas PM,Crumley S,Boku Y,Hanson G,Mourich DV,Kole R,Eckhaus MA,Gordon LB,Collins FS
Nat Med. 2021 Mar;27(3):536-545. doi: 10.1038/s41591-021-01274-0. Epub 2021 Mar 11
Koblan LW,Erdos MR,Wilson C,Cabral WA,Levy JM,Xiong ZM,Tavarez UL,Davison LM,Gete YG,Mao X,Newby GA,Doherty SP,Narisu N,Sheng Q,Krilow C,Lin CY,Gordon LB,Cao K,Collins FS,Brown JD,Liu DR
Nature. 2021 Jan;589(7843):608-614. doi: 10.1038/s41586-020-03086-7. Epub 2021 Jan 6
Mao X,Bharti P,Thaivalappil A,Cao K
Aging (Albany NY). 2020 Mar 18;12(6):5195-5208. doi: 10.18632/aging.102941. Epub 2020 Mar 18
Atchison L,Abutaleb NO,Snyder-Mounts E,Gete Y,Ladha A,Ribar T,Cao K,Truskey GA
Stem Cell Reports. 2020 Feb 11;14(2):325-337. doi: 10.1016/j.stemcr.2020.01.005. Epub 2020 Feb 6
Sun L,Chiang JY,Choi JY,Xiong ZM,Mao X,Collins FS,Hodes RJ,Cao K
Proc Natl Acad Sci U S A. 2019 Sep 17;116(38):18983-18993. doi: 10.1073/pnas.1907199116. Epub 2019 Sep 3