Caren Chang headshot
Contact Info
Office: 0128 Bioscience Research Bldg.
Phone: 301-405-1643
Caren Chang
Professor
Co-Director, Terrapin Teachers

Graduate Program Affiliations

  • BISI-Molecular & Cellular Biology (MOCB)  

Research Interests

We are focusing on signal transduction of the plant hormone ethylene (C2H4), a simple gas that has profound effects on plant growth and development. Our research utilizes a combination of molecular biology, genetics, cell biology and proteomics in order to understand the molecular mechanisms of ethylene signaling. Our model system is the small flowering plant Arabidopsis thaliana.

Education

  • Ph.D., California Institute of Technology, 1988

All Publications

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Latest Publications

Mou W,Khare R,Polko JK,Taylor I,Xu J,Xue D,Benfey P,Van de Poel B,Chang C,Kieber JJ
Ethylene-independent modulation of root development by ACC via downregulation of WOX5 and group I CLE peptide expression.
Proc Natl Acad Sci U S A. 2025 Feb 11;122(6):e2417735122. doi: 10.1073/pnas.2417735122. Epub 2025 Feb 5
Wang Y,Jiang L,Kong D,Meng J,Song M,Cui W,Song Y,Wang X,Liu J,Wang R,He Y,Chang C,Ju C
Ethylene controls three-dimensional growth involving reduced auxin levels in the moss Physcomitrium patens.
New Phytol. 2024 Jun;242(5):1996-2010. doi: 10.1111/nph.19728. Epub 2024 Apr 3
Li D,Dierschke T,Roden S,Chen K,Bowman JL,Chang C,Van de Poel B
A transporter of 1-aminocyclopropane-1-carboxylic acid affects thallus growth and fertility in Marchantia polymorpha.
New Phytol. 2022 Dec;236(6):2103-2114. doi: 10.1111/nph.18510. Epub 2022 Oct 19
Bharadwaj PS,Sanchez L,Li D,Enyi D,Van de Poel B,Chang C
The plant hormone ethylene promotes abiotic stress tolerance in the liverwort Marchantia polymorpha.
Front Plant Sci. 2022;13:998267. doi: 10.3389/fpls.2022.998267. Epub 2022 Oct 18
Brunkard JO,Chang C,Mayer BJ,Meyer C,Sheen J
ConducTORs of a Signaling Symphony: Metabolic and Hormone Responses Converge on TOR and EIN2 in plants.
Fac Rev. 2022;11:12. doi: 10.12703/r-01-000008. Epub 2022 May 10
Van de Poel B,Chang C
Is losing ethylene a losing game?
Mol Plant. 2022 May 2;15(5):788-790. doi: 10.1016/j.molp.2022.03.005. Epub 2022 Mar 12
Li D,Mou W,Van de Poel B,Chang C
Something old, something new: Conservation of the ethylene precursor 1-amino-cyclopropane-1-carboxylic acid as a signaling molecule.
Curr Opin Plant Biol. 2022 Feb;65:102116. doi: 10.1016/j.pbi.2021.102116. Epub 2021 Oct 13
Althiab-Almasaud R,Sallanon H,Chang C,Chervin C
1-Aminocyclopropane-1-carboxylic acid stimulates tomato pollen tube growth independently of ethylene receptors.
Physiol Plant. 2021 Dec;173(4):2291-2297. doi: 10.1111/ppl.13579. Epub 2021 Oct 13
Li D,Flores-Sandoval E,Ahtesham U,Coleman A,Clay JM,Bowman JL,Chang C
Ethylene-independent functions of the ethylene precursor ACC in Marchantia polymorpha.
Nat Plants. 2020 Nov;6(11):1335-1344. doi: 10.1038/s41477-020-00784-y. Epub 2020 Oct 26
Mou W,Kao YT,Michard E,Simon AA,Li D,Wudick MM,Lizzio MA,Feijó JA,Chang C
Ethylene-independent signaling by the ethylene precursor ACC in Arabidopsis ovular pollen tube attraction.
Nat Commun. 2020 Aug 14;11(1):4082. doi: 10.1038/s41467-020-17819-9. Epub 2020 Aug 14
Van Der Straeten D,Kanellis A,Kalaitzis P,Bouzayen M,Chang C,Mattoo A,Zhang JS
Editorial: Ethylene Biology and Beyond: Novel Insights in the Ethylene Pathway and Its Interactions.
Front Plant Sci. 2020;11:248. doi: 10.3389/fpls.2020.00248. Epub 2020 Mar 12
Nishiyama T,Sakayama H,de Vries J,Buschmann H,Saint-Marcoux D,Ullrich KK,Haas FB,Vanderstraeten L,Becker D,Lang D,Vosolsobě S,Rombauts S,Wilhelmsson PKI,Janitza P,Kern R,Heyl A,Rümpler F,Villalobos LIAC,Clay JM,Skokan R,Toyoda A,Suzuki Y,Kagoshima H,Schijlen E,Tajeshwar N,Catarino B,Hetherington AJ,Saltykova A,Bonnot C,Breuninger H,Symeonidi A,Radhakrishnan GV,Van Nieuwerburgh F,Deforce D,Chang C,Karol KG,Hedrich R,Ulvskov P,Glöckner G,Delwiche CF,Petrášek J,Van de Peer Y,Friml J,Beilby M,Dolan L,Kohara Y,Sugano S,Fujiyama A,Delaux PM,Quint M,Theißen G,Hagemann M,Harholt J,Dunand C,Zachgo S,Langdale J,Maumus F,Van Der Straeten D,Gould SB,Rensing SA
The Chara Genome: Secondary Complexity and Implications for Plant Terrestrialization.
Cell. 2018 Jul 12;174(2):448-464.e24. doi: 10.1016/j.cell.2018.06.033. Epub
Kim J,Yang R,Chang C,Park Y,Tucker ML
The root-knot nematode Meloidogyne incognita produces a functional mimic of the Arabidopsis INFLORESCENCE DEFICIENT IN ABSCISSION signaling peptide.
J Exp Bot. 2018 May 25;69(12):3009-3021. doi: 10.1093/jxb/ery135. Epub
Liu S,Yu F,Yang Z,Wang T,Xiong H,Chang C,Yu W,Li N
Establishment of Dimethyl Labeling-based Quantitative Acetylproteomics in Arabidopsis.
Mol Cell Proteomics. 2018 May;17(5):1010-1027. doi: 10.1074/mcp.RA117.000530. Epub 2018 Feb 13