Proteomics Core

Proteomics Core Facility

The Proteomics Core Facility is located in room 0109/0111 Biology-Psychology Building. The facility is equipped with a state-of-art ThermoFisher Orbitrap Fusion Lumos Tribrid mass spectrometer that is interfaced to a Dionex UltiMate3000 RSLCnano HPLC system. The facility also maintains 2 separate data stations dedicated for proteomics data processing, database searching, and generation of reports. Several popular software packages are installed on the data station with annual maintenance contract so that the Facility and its users always have access to the latest development in the field. Software packages include Proteome Discoverer, Mascot server, Scaffold, Seive, and Prosight PC. For protein separation, the Facility maintains an Agilent 3100 OFFGEL fractionator that performs isoelectric focusing based fractionation in solution. Peptide level fractionation can be achieved online with the Dionex U3000 HPLC or offline.

The Proteomics Core Facility is a fee for service facility supported by the College of Computer, Mathematical, and Natural Sciences (CMNS). The facility offers service to all researchers in the region, with priority given to users from the CMNS. Routine service includes molecular weight determination of intact proteins by LCMS and protein identification, and protein profiling of complex samples. Protein samples can be submitted as lyophilized powders, solutions, or gel slices. Please refer to the “How to prepare your samples” page below for detailed information.


The facility also welcomes collaborative research on projects beyond routine services. Please contact the facility director Dr. Yan Wang to initiate a collaborative research.




2225 Bioscience Research Building

4066 Campus Dr
College Park, MD 20742


0109/0111 Biology-Psychology Building
4094 Campus Drive
College Park, MD 20742


Tel: 301-405-6764 (office)

301-405-8425 (lab)



Check Dr. Wang’s availability

Availability of the Orbitrap Fusion Lumos