Sougata Roy

Associate Professor

Office Phone: (301)405-6158

Lab Phone: (301)405-2318

Lab: 2109 Bioscience Research Building

Office Address: 2110 Bioscience Research Building

Lab Website




Cell Biology





graduate program affiliations

  • BISI - BISI-Molecular & Cellular Biology (MOCB)
  • Physiological Systems (PSYS)

research interests

Cell-cell communication is the bandmaster that orchestrates an amazing transformation of a single-cell zygote into many different types of cells and organizes them into intricate patterns within the emerging body plan in a developing embryo. Our laboratory aims to understand how cells in multicellular organisms communicate with morphogenetic signals to coordinate in space and time and organize themselves to generate complex tissue architectures. Read more.
ResearchGate Lab page:





Recent lab news and recognitions:


recent publications


Drosophila FGF cleavage is required for efficient intracellular sorting and intercellular dispersal. Sohr A, Du L, Wang R, Lin L, Roy S. J Cell Biol. 2019. pii: jcb.201810138. doi: 10.1083/jcb.201810138. PubMed PMID: 30808704.


Ex vivo Drosophila Wing Imaginal Disc Culture and Furin Inhibitor Assay. Sohr A, Du L, Roy S. Bio-protocol. Vol 9, Iss 16, August 20, 2019.  DOI:   10.21769/BioProtoc.3336. 



Feedback regulation of cytoneme-mediated transport shapes a tissue-specific FGF morphogen gradient. Du L, Sohr A, Yan G, Roy S. Elife. 2018. doi: 10.7554/eLife.38137.


An efficient strategy for generating tissue-specific binary transcription systems in Drosophila by Genome Editing. Du L, Zhou A, Sohr A, Roy S. J Vis Exp. 2018. doi: 10.3791/58268.


Imaging cytonemes in Drosophila embryos. Du L, Roy S. Book chapter In: Morphogen Gradients, Methods in Molecular Biology, vol 1863. Humana Press, New York, NY; 2018.1863:29-45. doi: 10.1007/978-1-4939-8772-6_3. Erratum in: Methods Mol Biol. 2018;1863:E1.



Unique patterns of organization and migration of FGF-expressing cells during Drosophila morphogenesis. Du L, Zhou A, Patel A, Rao M, Anderson K, Roy S. Dev Biol. 2017 Jul 1; 427(1):35-48. doi: 10.1016/j.ydbio.2017.05.009.



Roy S,* and Kornberg T.B. Paracrine signaling mediated at cell-cell contacts. BioEssays 2015. 37(1): 25–33. (*, corresponding author; published online: 5 DEC 2014, DOI: 10.1002/bies.201400122). Video abstract:


Rao PR, Lin L, Huang H, Guha A, Roy S, Kornberg TB. Developmental compartments in the larval trachea of Drosophila. Elife. 2015 Oct 22;4. pii: e08666. doi: 10.7554/eLife.08666. PMID: 26491942    



Roy S, Huang H, Liu S and Kornberg TB. Cytoneme-mediated contact-dependent transport of the Drosophila Decapentaplegic signaling protein. Science, 2014. 343(6173):852, 1244624/


Kornberg TB, Roy S. Cytonemes as specialized signaling filopodia. Development, 2014. 141:729-736.


Kornberg TB, Roy S. Communicating by touch – neurons are not alone. Trends in Cell Biology, 2014. 24(6): 370-376 (Published online on 21st February, 2014; 10.1016/j.tcb.2014.01.003).



Roy S, Hsiung F, Kornberg TB. Specificity of Drosophila cytonemes for distinct signaling pathways.Science. 2011; 332(6027):354-8.


Roy S, Kornberg TB. Direct delivery mechanisms of morphogen dispersion. Science Signaling. 2011 22; 4 (200):pt8. 

Complete list of published work

Check: my bibliography; Google Scholar; and ORCID iD: 0000-0002-2236-9277 



Ph.D. 2006. Indian Institute of Science, Bangalore, India.

Post-doctoral fellowship (2006-2014). Department of Biochemistry and Cardiovascular Research Institute, University of California, San Francisco.