Latest Publications

Yuan R,Mariano M,Cachia D,Badar T,Patel SA
Modern Concepts in Precision Targeting of Acute Myeloid Leukemia Based on Principles of Molecular Oncology.
Cancers (Basel). 2026 Jul 19;18(14):. doi: 10.3390/cancers18142329. Epub 2026 Jul 19
Yuan R,Xie Y,Miron PM,Higgins AW,Hutchinson L,Cerny J,Patel SA
Clinico-genomic characterization of RAS-mutant acute myeloid leukemia.
Ann Hematol. 2026 Feb 9;105(3):99. doi: 10.1007/s00277-026-06843-2. Epub 2026 Feb 9
Yuan R,McGeehan A,Zhou S,Cheng C,Armanini M,Smith J,Embry M,Pena R,Lewis DK,Hernandez G,Bajjuri K,Tran C,Yin G,Abrahams C,Li X,Gerber HP,Yam A,Kiefel H
The Anti-FRα Antibody-Drug Conjugate Luveltamab Tazevibulin Demonstrates Efficacy in Non-Small Cell Lung Cancer Preclinical Models and Induces Immunogenic Cell Death.
Mol Cancer Ther. 2025 Sep 2;24(9):1428-1441. doi: 10.1158/1535-7163.MCT-24-0649. Epub
Bagchi S,Yuan R,Huang HL,Zhang W,Chiu DK,Kim H,Cha SL,Tolentino L,Lowitz J,Liu Y,Moshnikova A,Andreev O,Plevritis S,Engleman EG
The acid-sensing receptor GPR65 on tumor macrophages drives tumor growth in obesity.
Sci Immunol. 2024 Oct 18;9(100):eadg6453. doi: 10.1126/sciimmunol.adg6453. Epub 2024 Oct 18
King ME,Yuan R,Chen J,Pradhan K,Sariol I,Li S,Chakraborty A,Ekpenyong O,Yearley JH,Wong JC,Zúñiga L,Tomazela D,Beaumont M,Han JH,Eberlin LS
Long-chain polyunsaturated lipids associated with responsiveness to anti-PD-1 therapy are colocalized with immune infiltrates in the tumor microenvironment.
J Biol Chem. 2023 Mar;299(3):102902. doi: 10.1016/j.jbc.2023.102902. Epub 2023 Jan 13
Chikhale RV,Guneri D,Yuan R,Morris CJ,Waller ZAE
Identification of sugar-containing natural products that interact with i-motif DNA.
Bioorg Med Chem Lett. 2022 Oct 1;73:128886. doi: 10.1016/j.bmcl.2022.128886. Epub 2022 Jul 11
Reticker-Flynn NE,Zhang W,Belk JA,Basto PA,Escalante NK,Pilarowski GOW,Bejnood A,Martins MM,Kenkel JA,Linde IL,Bagchi S,Yuan R,Chang S,Spitzer MH,Carmi Y,Cheng J,Tolentino LL,Choi O,Wu N,Kong CS,Gentles AJ,Sunwoo JB,Satpathy AT,Plevritis SK,Engleman EG
Lymph node colonization induces tumor-immune tolerance to promote distant metastasis.
Cell. 2022 May 26;185(11):1924-1942.e23. doi: 10.1016/j.cell.2022.04.019. Epub 2022 May 6
Bagchi S,Yuan R,Engleman EG
Immune Checkpoint Inhibitors for the Treatment of Cancer: Clinical Impact and Mechanisms of Response and Resistance.
Annu Rev Pathol. 2021 Jan 24;16:223-249. doi: 10.1146/annurev-pathol-042020-042741. Epub 2020 Nov 16
Yuan R,Bhattacharya N,Kenkel JA,Shen J,DiMaio MA,Bagchi S,Prestwood TR,Habtezion A,Engleman EG
Enteric Glia Play a Critical Role in Promoting the Development of Colorectal Cancer.
Front Oncol. 2020;10:595892. doi: 10.3389/fonc.2020.595892. Epub 2020 Nov 13

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