Najib El-Sayed headshot
Contact Info
Office: 3128 Bioscience Research Bldg.
Phone: 301-405-2999
Najib M. El-Sayed
Professor
Director, Integrated Life Sciences Honors Program

Biography & Research Interests

Dr. Najib El-Sayed is a Professor of Cell Biology and Molecular Genetics at the University of Maryland, with a joint appointment in the Center for Bioinformatics and Computational Biology at UMIACS. He is the Director of Integrated Life Sciences (ILS) in the Honors College, Director of the Brain & Behavior Institute - Advanced Genomic Technologies Core (BBI-AGTC), and Director of Bioinformatics at the University of Maryland Institute for Health Computing.

He received his Ph.D. from Yale University in Molecular Parasitology and then trained as a Howard Hughes Medical Institute post-doctoral fellow in the laboratory of John Donelson at the University of Iowa. In 1998, he joined The Institute for Genomic Research (TIGR) in Rockville, Maryland where he led the sequencing, annotation, and comparative and functional genomic analyses of several human pathogens. He has been at the University of Maryland since 2006. He was the founding director of the Next-Generation Sequencing Core at the University, as well as the Computational Biology, Bioinformatics and Genomics graduate concentration area of studies.

Dr. El-Sayed’s research program is focused on the study of the biology of parasitism and host-pathogen interactions using genomic and bioinformatics approaches with the ultimate goal of better understanding infection and survival mechanisms. These approaches include the development and application of molecular, computational and genomic tools. In the long term, his research will contribute to better diagnosis, prevention and therapeutics of parasite- and bacteria-caused diseases in humans, animals and plants. He has published over 100 research papers and serves on several editorial boards. He also serves on NIH’s Genomics, Computational Biology and Technology (GCAT) study section as well as on the Scientific Advisory Board for the National Institute of Allergy and Infectious Diseases’ Genome Sequencing Centers for Infectious Diseases.


Teaching

  • BISI620: Bioinformatics and Genomics
  • BISI622: Programming for Biology
  • HLSC227: Topics in Scientific Integrity and Medical Ethics
  • HLSC280: Integrative and Quantitative Concepts in Biology
  • BSCI348R: Microbiology Internship

Graduate Program Affiliations


Education

  • Ph.D., Yale University School of Medicine, 1993

All Publications

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Latest Publications

Fernández OL,Belew AT,Rosales-Chilama M,Sánchez-Hidalgo A,Colmenares M,Saravia NG,El-Sayed NM
PLoS Negl Trop Dis. 2025 Oct;19(10):e0013600. doi: 10.1371/journal.pntd.0013600. Epub 2025 Oct 6
Gómez MA,Belew AT,Vargas DA,Giraldo-Parra L,Alexander N,Rebellón-Sánchez DE,Alexander TA,El-Sayed NM
Nat Commun. 2025 Apr 4;16(1):3235. doi: 10.1038/s41467-025-58330-3. Epub 2025 Apr 4
Fernández OL,Belew AT,Rosales-Chilama M,Sánchez-Hidalgo A,Colmenares M,Saravia NG,El-Sayed NM
bioRxiv. 2024 Nov 2;:. pii: 2024.10.29.620724. doi: 10.1101/2024.10.29.620724. Epub 2024 Nov 2
Augenstreich J,Poddar A,Belew AT,El-Sayed NM,Briken V
Biol Open. 2024 Sep 15;13(9):. doi: 10.1242/bio.060555. Epub 2024 Sep 19
Hart MT,Rom JS,Le Breton Y,Hause LL,Belew AT,El-Sayed NM,McIver KS
Infect Immun. 2024 Jun 11;92(6):e0008324. doi: 10.1128/iai.00083-24. Epub 2024 May 7
Augenstreich J,Poddar A,Belew AT,El-Sayed NM,Briken V
bioRxiv. 2024 Apr 11;:. pii: 2024.04.10.588863. doi: 10.1101/2024.04.10.588863. Epub 2024 Apr 11
Giraldo-Parra L,Rebellón-Sánchez DE,Navas A,Belew AT,El-Sayed NM,Gómez MA
J Immunol. 2024 Mar 1;212(5):894-903. doi: 10.4049/jimmunol.2300576. Epub
El Husseini N,Mekonnen SA,Hall CL,Cole SJ,Carter JA,Belew AT,El-Sayed NM,Lee VT
J Bacteriol. 2024 Jan 25;206(1):e0036123. doi: 10.1128/jb.00361-23. Epub 2023 Dec 4
Vargas DA,Gregory DJ,Koren RN,Zilberstein D,Belew AT,El-Sayed NM,Gómez MA
Front Parasitol. 2023;2:. pii: 1242727. doi: 10.3389/fpara.2023.1242727. Epub 2023 Oct 4
Mekonnen SA,El Husseini N,Turdiev A,Carter JA,Belew AT,El-Sayed NM,Lee VT
Proc Natl Acad Sci U S A. 2022 Dec 13;119(50):e2209383119. doi: 10.1073/pnas.2209383119. Epub 2022 Dec 5
Rom JS,Le Breton Y,Islam E,Belew AT,El-Sayed NM,McIver KS
Microorganisms. 2022 Aug 22;10(8):. doi: 10.3390/microorganisms10081686. Epub 2022 Aug 22
Burcham LR,Akbari MS,Alhajjar N,Keogh RA,Radin JN,Kehl-Fie TE,Belew AT,El-Sayed NM,McIver KS,Doran KS
mBio. 2022 Jun 28;13(3):e0098522. doi: 10.1128/mbio.00985-22. Epub 2022 Jun 6
Smith M,Yadav S,Fagunloye OG,Pels NA,Horton DA,Alsultan N,Borns A,Cousin C,Dixon F,Mann VH,Lee C,Brindley PJ,El-Sayed NM,Bridger JM,Knight M
PLoS Negl Trop Dis. 2021 Sep;15(9):e0009094. doi: 10.1371/journal.pntd.0009094. Epub 2021 Sep 8
Gomez MA,Belew AT,Navas A,Rosales-Chilama M,Murillo J,Dillon LAL,Alexander TA,Martinez-Valencia A,El-Sayed NM
Front Cell Infect Microbiol. 2021;11:687607. doi: 10.3389/fcimb.2021.687607. Epub 2021 Sep 7
Tavares TS,Mügge FLB,Grazielle-Silva V,Valente BM,Goes WM,Oliveira AER,Belew AT,Guarneri AA,Pais FS,El-Sayed NM,Teixeira SMR
Parasitology. 2021 Sep;148(10):1171-1185. doi: 10.1017/S0031182020002176. Epub 2020 Nov 16
Lee VT,Ghodssi R,El-Sayed NM,Malik RD,Goloubeva OG,Hazen TH,Rasko DA
Microbiol Resour Announc. 2020 Nov 12;9(46):. doi: 10.1128/MRA.00978-20. Epub 2020 Nov 12
Burcham LR,Le Breton Y,Radin JN,Spencer BL,Deng L,Hiron A,Ransom MR,Mendonça JDC,Belew AT,El-Sayed NM,McIver KS,Kehl-Fie TE,Doran KS
mBio. 2020 Nov 10;11(6):. doi: 10.1128/mBio.02302-20. Epub 2020 Nov 10
Hamidzadeh K,Belew AT,El-Sayed NM,Mosser DM
Blood Adv. 2020 Nov 10;4(21):5460-5472. doi: 10.1182/bloodadvances.2020002683. Epub
Oliveira AER,Pereira MCA,Belew AT,Ferreira LRP,Pereira LMN,Neves EGA,Nunes MDCP,Burleigh BA,Dutra WO,El-Sayed NM,Gazzinelli RT,Teixeira SMR
PLoS Pathog. 2020 Aug;16(8):e1008781. doi: 10.1371/journal.ppat.1008781. Epub 2020 Aug 18
Dalby E,Christensen SM,Wang J,Hamidzadeh K,Chandrasekaran P,Hughitt VK,Tafuri WL,Arantes RME,Rodrigues IA,Herbst R,El-Sayed NM,Sims GP,Mosser DM
J Immunol. 2020 Jul 1;205(1):102-112. doi: 10.4049/jimmunol.1901382. Epub 2020 May 20