Anwar Huq

Research Professor 

 

Contact

Emailhuq@umd.edu or huqanwar@gmail.com

Office Phone: (301) 405-7428

Office Address: Bioscience Research Building #413, Room 3132


research interests

Understanding the survival, multiplication and transmission of pathogens that   are autochthonous in the environment targeted for disease prevention and intervention. Climate has significant impact on the occurrence, survival, multiplication of environmental organisms and its ability to cause disease. Studying waterborne pathogens, primary focusing on Vibrio cholerae, which is the causative agent of cholera. Conventional bacteriological, immunological and molecular methods, as well as bioinformatics and satellite remote sensing are being employed to develop a global prediction model with the ultimate goal to prevent cholera. Safe drinking water has also been a focus in my research and a simple filtration method for safe drinking water was developed, which has been proven to save lives and prevent suffering in an extensive clinical field trial carried out in Bangladesh.  

 

recent publications

Janelidze N., E. Jaiani, N Lashkhi, A. Tskhvediani, T. Kokashvili, T. Gvarishvili, D. Jgenti, E. Mikashavidze, R. Diasmidze, S. Narodny, R. Obiso, C.A. Whitehouse, A. Huq, M. Tediashvili. 2011. Microbial water quality of the Georgian coastal zone of the Black Sea. Mar Pollut Bull. 62(3):573-580.

Constantin de Magny G., P. K. Mozumder, C. J. Grim, N. A. Hasan, M. N. Naser, M. Alam, R. B. Sack, A. Huq, R. R. Colwell. 2011. Role of Zooplankton Diversity in Vibrio cholerae Population Dynamics and in the incidence of Cholera in the Bangladesh Sundarbans: Appl Environ Microbiol.77:6125-6132 DOI:10.1128/AEM.01472-10]

Mozumdar, P. K., N. Naser, M. Alam and A. Huq. 2011. Abundance and Seasonal Diversity of Zooplankton in Coastal Aquatic Environments of Mathbaria, Bangladesh. J. Dhaka Univ. I. Biol. Sci. 20(2):163-171.

 

Akanda, A.S., A.S. Jutla, M. Alam, g. Constantine de Magny, A. K. Siddique, R.B. Sack, A. Huq, R.R. Colwell and S. Islam, 2011. “Hydroclimatic Influences on Seasonal and Spatial Cholera Transmission Cycles: Implications for Public Health Intervention in the Bay of Bengal”. Water Resources Res, 47:1-11. Doi:10.1029/2010WR009914

 

Kirschner, A., K. T., S. Schauer, B. Steinberger, I. Wilhartitz, C. J. Grim, A. Huq, R. R. Colwell, A. Herzig, and R. Sommer. 2011. Interaction of Vibrio cholerae non-O1/non- O139 with Copepods, Cladocerans and Competing Bacteria in the Large Alkaline Lake Neusiedler See, Austria. Environ. Microbiol. 61:496-506. DOI: 10.1007/s00248-010-9764-9

 

Alam, M., A. Islam, N. A. Bhuiyan, N. Rahim, A. Hossain, G. Y. Khan, D. Ahmed, H. Watanabe, H. Izumiya, A. S. G. Faruque, A. S. Akanda, S. Islam, R. B. Sack, A. Huq, R. R. Colwell, A. Cravioto. 2011. Clonal transmission, dual peak, and off-season cholera in Bangladesh. Infect. Ecol. and Epidemiol. 1:1-11. DOI: 10.4302/iee.v1i0.7273.

 

Mozumder, P. K., M. N. Naser, M. Alam, R. B. Sack, R. R. Colwell and A. Huq. 2011. Taxonomical study of the rotifera fauna of Mathbaria in Southern part of Bangladesh.Bangladesh J. Zool. 39(1):1-10.

 

Haley, B. J., A. Chen, C. J. Grim, P. Clark, C. M. Diaz, E. Taviani, N. A. Hasan, E. Sancomb, W. Mahmoud Elnemr, M. A. Islam, A. Huq, R. R. Colwell and E. Benediktsdóttir. 2012. Vibrio cholerae in an Historically Cholera Free Country. Environ. Microbiol. Rep. DOI: 10.1111/j.1758-2229.2012.00332.x

 

Nahar S, Sultana M, Naser MN, Nair GB, Watanabe H, Ohnishi M, Yamamoto S, Endtz H, Cravioto A, Sack RB, Hasan NA, Sadique A, Huq A, Colwell RR, Alam M. 2012. Role of Shrimp Chitin in the Ecology of Toxigenic Vibrio cholerae and Cholera Transmission. Front Microbiol. 2012;2:260. Epub 2012 Jan 4.

 

Banakar, V., G. Constantin de Magny, J. Jacobs, R. Murtugudde, A. Huq, B. Wood, and R. Colwell. 2012. Temporal and spatial variability in the distribution of Vibrio vulnificus in the Chesapeake Bay: A Hindcast study. EcoHealth. DOI: 10.1007/s10393-011-0736-4.

 

Gurbanov S., R. Akhmadov, G. Shamkhalova, S. Akhmadova, B. J. Haley, R. R. Colwell and A. Huq. Occurrence of Vibrio cholerae in Municipal and Natural Waters and Incidence of Cholera in Azerbaijan. 2012. J. Ecohealth. 8(4):468-77. doi: 10.1007/s10393-012-0756-8

 

Stauder, M., A. Huq, E. Pezzati, C. J. Grim, P. Ramoino, L. Pane, R. R. Colwell, C. Pruzzo and L. Vezzulli. 2012. Role of GbpA protein, an important virulence-related colonization factor, for Vibrio cholerae’s survival in the aquatic environment. Environmental Microbiol. Rep. doi:10.1111/j.1758-2229.2012.00356.x

 

Hasan, N. A., S. Y. Choi, M. Eppinger, J. B. Prosper, P. W. Clark, M. Alam, A. Chen, E. Taviani, B. Haley J. Jakupciak, H. Lee, S. Lansing, M. McDonald, A. Cravioto, A. Huq, J. Ravel, T. Cebula, and R. R. Colwell. 2012. A closer inspection of Haitian Cholera Outbreak 2010. PNAS, 109 (29) E2010–E2017. doi/10.1073/pnas.1207359109.

 

Rashid, A., B. J. Haley, M. Rajabov, S. Ahmadova S. Gurbanov, R. Colwell, A. Huq. Detection of Vibrio cholerae in Environmental Waters Including 1 Drinking Water Reservoirs of Azerbaijan. 2012. Environmental Microbiol Reports. DOI: 10.1111/j.1758- 2229.2012.00369.

 

Taviani, E., M. Spagnoletti, D. Ceccarelli, B. J. Haley, N. A. Hasan, A. Chen, M. M. Colombo, A. Huq and R. R. Colwell. 2012. Genomic analysis of ICEVchBan8: Anatypical genetic element in Vibrio cholerae. FEBS Letter. 586(11): 1617–1621.

 

Johnson, C. N., J. C. Bowers, K. J. Griffitt, V. Molina, R. W. Clostio, S. Pei, E. Laws, R. N. Paranjpye, M. S. Strom, A. Chen, N. A. Hasan, A. Huq, N. F. Noriea III, D. J. Grimes, and R. R. Colwelle. 2012. Ecology of Vibrio parahaemolyticus and Vibrio vulnificus in the Coastal and Estuarine Waters of Louisiana, Maryland, Mississippi, and Washington (United States). Appl Environ. Microbiol. 78(20):7249–7257. DOI:10.1128/AEM.01296-12.

 

Rashed, S. M., S. B. Mannan, F. Johura, M. T. Islam, A. Sadique, H. Watanabe, R. B.Sack, A. Huq, R. R. Colwell, A. Cravioto, and M. Alam. 2012. Genetic Characteristics of Drug Resistant V. cholerae O1 Causing Endemic Cholera in Dhaka, 2006-2011. J. Med Microbiol. 61:1736-1745. doi:10.1099/jmm.0.049635-0.

 

Hasan, N. A, S. Y. Choi, M. Alam, A .Cravioto, A. Huq, T. A. Cebula, & R. R. Colwell. 2012. Reply to Mekalanos et al.: Genomic diversity of Vibrio cholerae. Proc Natl Acad Sci, 109(47), E3207-E3207.

 

Hasan, N. A, S. Y. Choi, M. Alam, A .Cravioto, A. Huq, T. A. Cebula, & R. R. Colwell. 2012. Reply to Frerichs et al.: Chasing the genetic diversity, not source attribution. Proc Natl Acad Sci,109(47), E3209-E3209.

 

Chomvarin C, F. T. Johura, S.B. Mannan, W. Jumroenjit, B. Kanoktippornchai, W. Tangkanakul, N. Tantisuwichwong, S. Huttayananont, H. Watanabe, N.A. Hasan, A. Huq, A. Cravioto, R. Colwell, M. Alam. 2013. Drug response and genetic properties of Vibrio cholerae associated with endemic cholera in Northeastern Thailand, 2003- 2011. J Med Microbiol. doi:10.1099/jmm.0.053801-0

 

Jutla, A., A. Akanda, A. Huq, A. G. Farouque, R. Colwell and S Islam. 2013. A water marker monitored by satellites to predict seasonal endemic cholera. J. Remote Sensing Letters, 4(8):822–831. doi.org/10.1080/2150704X.2013.802097

 

Rowe, I, M. Elahi, A. Huq, and S. Sukharev. 2013. The mechanoelectrical response of the cytoplasmic membrane of Vibrio cholerae. J. Gen Physiol. 142:75-85. www.jgp.org/cgi/doi/10.1085/jgp.201310985.

 

Jaiani E, T. Kokashvili , N. Mitaishvili, T. Elbakidze, N. Janelidze, N. Lashkhi, R. Kalandadze, E. Mikashavidze, G. Natroshvili , C. A. Whitehouse, A. Huq, M. Tediashvili. 2013. Microbial water quality of recreational lakes near Tbilisi, Georgia. J Water Health, 11(2):333-345. doi: 10.2166/wh.2013.057.

 

Akanda, Ali, A. Jutla, D. Gute, R. Sack, M. Alam, A. Huq, R. Colwell, and S. Islam. 2013. Population Vulnerability to Biannual Cholera Outbreaks and Associated Macro- Scale Drivers in Bengal Delta. Amer. J. Trop. Med Hyg, pp 89(5):950-959. doi:10.4269/ajtmh.12-0492

 

Jutla, A., E. Whitcombe, N. Hasan, B. Haley, A. Akanda, A. Huq , M. Alam, B. Sack, R. Colwell. 2013. Environmental Factors Influencing Epidemic Cholera. Amer. J. Trop. Med. & Hyg. 07/2013; DOI:10.4269/ajtmh.12-0721.

 

Alam, M., S. M Rashed, S. B. Mannan, T. Islam, M. L. Lizarraga-Partida, G. Delgado, R. Morales., J. L. Mendez, A. Navarro, H. Watanabe, M. Ohnishi, N. A. Hasan. A. Huq, G. B. Nair, R. B. Sack, R. R. Colwell, and A. Cravioto. 2013. Vibrio cholerae CTX+ El Tor with an additional Truncated CTX Prophage Displaces Classical and Altered El Tor in Mexico, 1998 – 2008. J. Emerging Infect Dis.

 

Hasan, A. N., D. Ceccarelli, C. J. Grim, E. Taviani, J. Choi, A. Sadique, M. Alam, A. K. Siddique, R. B. Sack, A. Huq, and R. R. Colwell. 2013. Distribution of virulence genes in clinical and environmental Vibrio cholerae in Bangladesh. App Environ. Microbiol. 79(18):5782. doi: 10.1128/AEM.01113-13.

 

Rashed, S. M., A. Iqbal, S B. Mannan, T. Islam, M. Rashid, F. Johura, H. Watanabe, N. A. Hasan, A. Huq, O. C. Stine, R. B. Sack, R. R. Colwell, and M. Alam. 2013. Vibrio cholerae O1 El Tor and O139 Bengal Strains Carrying ctxBET, Bangladesh. J. Emerging Infect. Dis, 19(10):1713-1715.

 

Ceccarelli, D., M. Spagnoletti, N. A. Hasan, S. Lansing, A. Huq, and R. R. Colwell. 2013. A new Integrative Conjugative Element Detected in Haitian Isolates of Vibrio cholerae non-O1/non-O139. Res Microbiol. 164(9):891-893. doi:10.1016/j.resmic.2013.08.004.

 

Haley, B. J., S. Y. Choi, N. A. Hasan, A. S. H. Abdullah, T. A. Cebula, A. Huq, R. R. Colwell. 2013. Genome Sequences of Clinical Vibrio cholerae Isolates from an Oyster- borne Cholera Outbreak, Florida, USA. Appl. Environ. Microbiol. doi:10.1128/genomeA.00966-13.

 

Ceccarelli, D., N. A. Hasan, A. Huq, R. R. Colwell. 2013. Virulence factors of epidemic and pandemic Vibrio parahaemolyticus. Frontiers in Cellular and Infect Microbiol. 3: 97 http://www.frontiersin.org/cellular_and_infection_microbiology/editorialboard

 

Chomvarin, C., W. Jumroenjit, W. Namwat, W. Tangkanakul, N. A. Hasan, K. Chaicumpar, K. Faksri, and A. Huq. 2014. Genotype and Drug Resistance of Clinical and Environmental Vibrio cholerae non-O1 and non-O1/O139 in Northern Thailand. The Southeast Asian J Trop Med and Pub Hlth. 45(6):1-11.

 

Rashed, S. M., A. S. Azman, M. Alam, S. Li, D. A. Sack, J. G. Morris, Jr., I. Longini, A. K. Siddique, A. Iqbal, A. Huq, R. R. Colwell, R. B. Sack, O. C. Stine. 2014. Genetic Analysis of Vibrio cholerae in the Human Population of Two Rural Communities in Bangladesh During Outbreaks. J. Emerging Infect. Dis. doi.org/10.3201/eid2001.130796

 

Haley, B. J., T. Kokashvili, A. Tskshvediani, N. Janelidze, N. Mitaishvili, C. J. Grim, G. C.n de Magny, A. J. Chen, E. Taviani, T. Eliashvili, M. Tediashvili, C. Whitehouse, R. R Colwell, and A. Huq. 2014. Molecular Diversity and Predictability of Vibrio parahaemolyticus along the Georgian Coastal Zone of the Black Sea. Front. Microbiol. 10 February 2014 | doi: 10.3389/fmicb.2014.00045

 

Alam, M., S. M. Rashed, S. B. Mannan, T. Islam, L. Lizarraga-¬Partida, G. Delgado, R. Morales., J. L. Mendez, A. Navarro., H. Watanabe, M. Ohnishi, N. A. Hasan, A. Huq, R. B. Sack, R. R. Colwell, and A. Cravioto. 2014. Occurrence in Mexico, 1998 – 2008, of Vibrio cholerae CTX+ El Tor Carrying an Additional Truncated CTX Prophage. Proc Nat Acd, Sc. 111(27):9917-9922, Jul 8. doi: 10.1073/pnas.1323408111

 

Hasan, N. A., T. Rezayat, p. Blatz, S. Y. Choi, K. J. Griffitt, S. M. Rashed, A. Huq, , N. Conger, R. R. Colwell, and D. J. Grimes. 2014. Non-toxigenic Vibrio cholerae non-O1/O139 Isolated from a Gulf Coast Case of Human Gastroenteritis. J. Clin. Microbiol. October, 2014. doi: 10.1128/JCM.02187-14.

 

Urquhart, E. A., B. F. Zaitchika, S. D. Guikemab, B. J. Haley, E. Taviani, A. Chen, M. E. Brown, A. Huq, R. R. Colwell. 2015. Use of Environmental Parameters to Model Pathogenic Vibrios in Chesapeake Bay. J Environmental Informatics. 26(1):1-13.doi:10.3808/jei.201500307

 

Kahler, A.M., B. J. Haley, A. Chen, B. J. Mull, C. L. Tarr, M. Turnsek, L. Katz, M. S. Humphrys, N. Freeman, J. Boncy, R. R. Colwell, A. Huq, and V. R. Hill. 2015. Environmental Surveillance for Toxigenic Vibrio cholerae in Surface Waters of Haiti. Amer. J. Trop. Med Hyeg. 92(1): 118-125. doi:10.4269/ajtmh.13-0601

 

Jutla, A., A. Huq and R. R. Colwell. 2015. Diagnostic approach for monitoring hydroclimatic conditions related to emergence of West Nile virus in West Virginia. Front. Pub. Hlth. 3:10. doi: 10.3389/fpubh.2015.00010

 

Ceccarelli, D., A. Chen, N. Hasan, S. Rashed, A. Huq, and R. Colwell. 2015. Vibrio cholerae non-O1/non-O139 carrying multiple virulence factors and V. cholerae O1 in the Chesapeake Bay, Maryland. Appl. Environ. Microbiol. 81(6):1909-18. doi:10.1128/AEM.03540-14

 

Hasan, N. A., C. J. Grim , E. K Lipp , I. N.G. Rivera , J. Chun, B. J. Haley , E. Taviani , S. Y. Choi , M. l Hoq , C. Munk , T. S. Brettin , D. Bruce , J. F. Challacombe , C. Detter ,C. S. Han, J. A Eisen , A. Huq , R. R. Colwell. 2015. Deep-sea Hydrothermal Vent Bacteria Related to Human Pathogenic Vibrio Species. Proc. Nat. Acad. Sc. May 112(21):E2813- 9. doi: 10.1073/pnas.1503928112

 

Nasr-Azadani, Fariborz, A. Unnikrishnan, A. Akanda, S. Islam, M. Alam, A. Huq, A. Jutla, R. Colwell. 2015. A framework for downscaling river discharge to assess the effects of climate change on endemic cholera. J. Climate Res. doi: 10.3354/cr01310

 

Assadi, M., P. Chamanrokh, C. A. Whitehouse, A. Huq. 2015. Methods for Detecting the Environmental Coccoid Form of Helicobacter pylori. Front Public Health. May 28(3):147. doi: 10.3389/fpubh.2015.00147

 

Jutla, Antarpreet, H. Aldach, H. Billian, R. Posa, A. Akanda, A. Huq, R. Colwell. 2015. Satellite based assessment of hydroclimatic conditions related to cholera in Zimbabwe. PLoS One.DOI:10.1371/journal.pone.0137828.

 

Kokashvili, T., C. A. Whitehouse, A.Tskhvediani, C. J. Grim, T. Elbakidze, N. Mitaishvili, N. Janelidze, E. Jaiani, B. J. Haley, N. Lashkhi, A. Huq, R. R. Colwell and M. Tediashvili. 2015. Occurrence and diversity of clinically important Vibrio species in the aquatic environment of Georgia. Front. J. Pub. Hlth. doi: 10.3389/fpubh.2015.00232.

 

Jutla, A., A. Ali, A. Unnikrishnan, W. Palaash, A. Huq, R. Colwell. 2015. Predictive Time Series Analysis Linking Bengal Cholera with Terrestrial Water Storage Measured from Gravity Recovery and Climate Experiment Sensors. Amer J Trop Med Hyg, 93(6):(#J. Nature Geoscience. DOI: 10.4269/ajtmh.14-0648

 

Choi, S. Young, S. M. Rashed, N. A. Hasan, M. Alam, T. Islam, A. Sadique, F. Johura, M. Eppinger, J. Ravel, A. Huq, A. Cravioto, R. R. Colwell. 2016. Phylogenetic Diversity of Vibrio cholerae Associated with Endemic Cholera in Mexico from 1991 to 2008. mBio 7(2):e02160-15. DOI:10.1128/mBio.02160-15